Atorvastatin is a prescription medication in the statin class. It is one of the most commonly prescribed drugs for lowering cholesterol and reducing the risk of cardiovascular disease.
Doctors commonly prescribe atorvastatin to:
- Lower LDL (“bad”) cholesterol
- Reduce triglycerides (a type of blood fat)
- Slightly increase HDL (“good”) cholesterol
- Reduce the risk of heart attack and stroke
- Help prevent cardiovascular events in people with conditions such as diabetes or established heart disease, or in those at high cardiovascular risk.
It works by blocking an enzyme in the liver called HMG-CoA reductase, which the body uses to make cholesterol. As a result, the liver produces less cholesterol and removes more LDL cholesterol from the bloodstream.
Common side effects
Most people tolerate atorvastatin well, but possible side effects include:
- Muscle aches or soreness
- Joint pain
- Headache
- Digestive symptoms such as nausea or diarrhea
Rare but important side effects
Seek medical advice promptly if you develop:
- Severe muscle pain or weakness, especially with dark-colored urine
- Yellowing of the skin or eyes (jaundice)
- Unusual fatigue or signs of liver problems
While taking atorvastatin
- Continue following a heart-healthy diet and exercise plan if recommended by your healthcare provider.
- Take the medication exactly as prescribed.
- Tell your doctor about all other medications and supplements you use, as some can interact with atorvastatin.
- Avoid large amounts of grapefruit or grapefruit juice, as they can increase atorvastatin levels in the body and raise the risk of side effects.
For many people with high cholesterol or elevated cardiovascular risk, atorvastatin is an effective, well-studied medication that significantly lowers the risk of heart attack and stroke when used appropriately.
