A headline like “Eight pills you shouldn’t take because they damage your kidneys” is misleading. Many medications can affect the kidneys under certain circumstances, but they are often safe and effective when used as directed and with appropriate monitoring.
Here are eight types of medications that are commonly associated with kidney problems if misused or in susceptible people:
- Ibuprofen and other NSAIDs (such as Naproxen)
- Can reduce blood flow to the kidneys, especially in older adults, people with kidney disease, dehydration, or heart failure.
- Diclofenac
- Another NSAID with similar kidney risks, particularly with long-term or high-dose use.
- Gentamicin
- An antibiotic that can be toxic to the kidneys, but it is usually given with careful dosing and monitoring.
- Vancomycin
- Another antibiotic that may affect kidney function, especially at high blood levels or when combined with other kidney-toxic drugs.
- Lithium
- Used to treat certain mental health conditions. Long-term use requires regular kidney function tests.
- Tacrolimus
- An immunosuppressant that can affect the kidneys, so doses are carefully adjusted and monitored.
- Cyclosporine
- Another immunosuppressant with potential kidney side effects that requires ongoing monitoring.
- Some chemotherapy medicines, such as Cisplatin
- Can damage the kidneys, but healthcare teams use hydration and monitoring to reduce the risk.
Who is at higher risk?
Kidney side effects are more likely if you:
- Already have kidney disease.
- Are dehydrated.
- Are older.
- Take several medications that affect the kidneys.
- Have conditions such as diabetes or high blood pressure.
Protecting your kidneys
- Take medications only as directed.
- Stay well hydrated unless your clinician has advised you to limit fluids.
- Tell your healthcare provider about all prescription, over-the-counter, and herbal products you use.
- Have kidney function checked if you’re taking medications that require monitoring.
Bottom line: Don’t stop a prescribed medication because of a viral post. If you’re concerned about a medicine’s effect on your kidneys, discuss it with your healthcare provider or pharmacist—they can help weigh the benefits and risks and recommend alternatives if needed.
