Claims like “these 5 medications increase the risk of heart attack and stroke” often circulate online, but the reality is more nuanced: some medications can increase cardiovascular risk in certain older adults, especially with specific conditions, doses, or combinations. They should not be stopped suddenly without medical advice.
Examples of medication categories that may require extra caution in older adults include:
- Certain nonsteroidal anti-inflammatory drugs (NSAIDs)
- Examples: ibuprofen or naproxen (especially at higher doses or long-term use).
- May raise blood pressure and can increase the risk of heart attack or stroke in some people, particularly those with existing heart disease.
- Some diabetes medications or combinations that can cause low blood sugar
- Severe episodes of low blood sugar can put stress on the heart and may be dangerous in older adults.
- Certain decongestants
- Ingredients such as pseudoephedrine can raise blood pressure and heart rate and may be risky for people with uncontrolled hypertension or heart conditions.
- Some stimulant medications
- These can increase heart rate and blood pressure and require careful monitoring in people with cardiovascular risk.
- Certain hormone therapies
- Some forms of estrogen-containing therapy may increase the risk of blood clots and stroke in some older individuals, depending on age, timing, and health history.
Other medications can also affect heart rhythm, blood pressure, bleeding risk, or fluid balance, which may influence cardiovascular health.
Important: A medication being on a caution list does not mean it is unsafe for everyone. Doctors weigh the benefits and risks based on the person’s medical history, other medicines, and risk factors.
If you share the names of the medications you’re concerned about (or a list of your current medicines), I can explain what heart-related risks are known and what questions to ask your doctor.
