Amlodipine is a commonly prescribed medication for high blood pressure and certain heart conditions. Many people tolerate it well, but side effects can occur — especially when starting treatment or increasing the dose.
Here are 12 of the more common side effects and what to watch for:
- Swelling in the ankles or feet (edema)
This is one of the most common side effects. Fluid can build up in the lower legs, causing puffiness or tight shoes. - Headache
Blood vessel relaxation can sometimes trigger mild to moderate headaches, especially early on. - Dizziness or lightheadedness
Because the medication lowers blood pressure, some people feel dizzy when standing up quickly. - Flushing or warmth in the face
Widened blood vessels can cause redness or a warm sensation. - Fatigue or tiredness
Some people report low energy or sleepiness. - Heart palpitations
You may notice a fast, pounding, or irregular heartbeat. - Nausea or upset stomach
Mild digestive symptoms can occur, though they are usually temporary. - Abdominal pain
Some users experience stomach discomfort or cramping. - Sleepiness or drowsiness
This can affect concentration or driving in some people. - Muscle cramps or aches
Less common, but some patients report muscle discomfort. - Gum swelling (gingival hyperplasia)
Long-term use can occasionally cause the gums to enlarge or become tender. - Low blood pressure (hypotension)
Symptoms can include fainting, weakness, blurred vision, or severe dizziness.
When to seek medical help
Contact a healthcare professional promptly if you experience:
- Severe swelling
- Chest pain
- Fainting
- Shortness of breath
- Very rapid heartbeat
- Signs of an allergic reaction (rash, swelling of face/tongue, trouble breathing)
Important notes
- Do not stop taking amlodipine suddenly unless your doctor tells you to.
- Side effects are often dose-related; sometimes adjusting the dose helps.
- Combining it with other blood pressure medications can increase dizziness or swelling.
For official prescribing and safety information, see:
Pfizer prescribing information for Norvasc (amlodipine)
