8 Types of Pills That May Harm Your Kidneys — What to Know
The kidneys filter waste and help balance fluids, minerals, and medicines in your body. Some medications can affect kidney function, especially when taken at high doses, for a long time, or in people who already have kidney problems.
Do not stop any prescribed medication without speaking with a healthcare professional. The goal is to understand risks and use medicines safely.
1. Nonsteroidal anti-inflammatory drugs (NSAIDs)
Common examples:
- Ibuprofen
- Naproxen
- Diclofenac
These pain relievers can reduce blood flow to the kidneys in some people, especially with:
- Long-term use
- High doses
- Dehydration
- Existing kidney disease
2. Certain antibiotics
Some antibiotics can affect the kidneys, particularly in people with reduced kidney function or when doses are not adjusted properly.
Examples include certain:
- Aminoglycosides
- Other antibiotics requiring kidney monitoring
3. Some blood pressure medicines (in certain situations)
Medicines such as ACE inhibitors and ARBs can change kidney function tests. They are often kidney-protective for many people, especially those with diabetes, but doctors may monitor kidney function and potassium levels.
4. Diuretics (“water pills”)
Diuretics help remove extra fluid from the body. They are commonly used for high blood pressure and heart conditions.
Possible kidney concerns:
- Dehydration
- Changes in electrolytes
- Reduced kidney function if fluid loss is excessive
5. Certain acid-reducing medications
Some long-term use of certain proton pump inhibitors (PPIs) has been associated with kidney problems in some studies.
Examples include medicines used for:
- Acid reflux
- Stomach ulcers
Use them only as directed and review long-term use with a healthcare professional.
6. Some antiviral medications
Certain antiviral drugs may require kidney monitoring because they are processed through the kidneys or can affect kidney function in some situations
