The claim “Eight pills you shouldn’t take because they damage your kidneys” is often presented as a scare headline. The reality is more nuanced: some medications can affect kidney function in certain people, especially at high doses, with long-term use, during dehydration, or when combined with other medicines. Many of these drugs are also very important and safe when used correctly under medical guidance.
Examples of medications that may require caution include:
1. Nonsteroidal anti-inflammatory drugs (NSAIDs)
Examples: ibuprofen and naproxen
- Can reduce blood flow to the kidneys and may cause kidney injury, especially in people with kidney disease, dehydration, heart failure, or older adults.
2. Certain antibiotics
- Some antibiotics can affect kidney function, particularly in people with existing kidney problems or when used at high doses.
- Doctors adjust doses based on kidney function when needed.
3. Some blood pressure medicines
- Certain medicines that affect the kidney’s blood-flow regulation may change kidney lab results and require monitoring, especially when starting treatment or changing doses.
4. Diuretics (“water pills”)
- These help remove extra fluid but can contribute to dehydration or electrolyte changes if not properly managed.
5. Some acid-reducing medications
- Certain long-term acid-suppressing medicines have been associated in studies with kidney problems in some people, though the absolute risk varies.
6. Some chemotherapy and immune-related medicines
- These can affect the kidneys, which is why doctors monitor kidney function during treatment.
7. High-dose supplements or herbal products
- Some supplements can contain ingredients that may stress the kidneys or interact with medicines.
8. Certain contrast agents used in medical imaging
- Some people with reduced kidney function need special precautions before receiving
